Physician profile
Ryan D Knake
NPI 1063805745
$680.39
in general payments reported to CMS, 2019-2025
13 companies · $78.40 in 2025
The $78.40 reported for 2025 was less than what a typical Physician Assistant provider received nationally (typical 2025 total: $183).
Payments by year
General payments by program year, as reported to CMS.
General payments by year: 2021: $228 · 2022: $193 · 2023: $83.26 · 2024: $97.27 · 2025: $78.40.
What the payments were for
Nature of payment as categorized by the reporting companies: meals, consulting, travel, and so on.
Food and Beverage: $259.
View as a table
| Payment type | Amount (2023-2025) |
|---|---|
| Food and Beverage | $258.93 |
Payment-type detail covers 2023-2025; earlier years are included in totals but not broken out here.
Who reported paying
General payments only, as reported to CMS. Product names cover 2023-2025.
| Company | General payments | Years | Top products |
|---|---|---|---|
| Novocure INC. | $186.98 | 2021-2025 | Optune Gio, Optune |
| Pfizer INC. | $119.12 | 2021-2024 | |
| Janssen Biotech, INC. | $78.36 | 2021-2024 | Erleada |
| Blue Earth Diagnostics | $49.02 | 2021 | |
| Bayer Healthcare Pharmaceuticals INC. | $46.85 | 2021-2022 | |
| Myriad Genetic Laboratories, INC. | $36.83 | 2022-2024 | Prolaris |
| Dendreon Pharmaceuticals LLC | $32.12 | 2021 | |
| Astrazeneca Pharmaceuticals Lp | $25.60 | 2025 | Imfinzi |
| Boston Scientific Corporation | $24.97 | 2022 | |
| Tolmar Pharmaceuticals, INC. | $23.40 | 2022 | |
| Bioprotect Medical, INC. | $23.38 | 2025 | Bioprotect Balloon Implant System |
| Sumitomo Pharma America, INC. | $17.53 | 2023 | Orgovyx |
| Astellas Pharma US INC | $16.23 | 2021 |
Drugs and devices associated with these payments
CMS records which products a payment was associated with, not how the money was allocated. Association is not allocation: one payment can be associated with several products, and a product listing does not mean the payment was made because of that product. Product detail covers 2023-2025.
If you want to bring it up
Most clinicians are glad to talk about this. A respectful way in:
- "I saw Ryan Knake listed in the CMS Open Payments database. Can you tell me about your work with those companies?"
- "Is there a generic or alternative to this medication, and would it work as well for me?"
- "What made you choose this particular treatment for my situation?"
These are normal questions. A good clinician will welcome them.
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Source: CMS Open Payments, program years 2019-2025, as reported to CMS by drug and device makers (published June 30, 2026). Drug and device detail covers 2023-2025.